منابع مشابه
Opioids in chronic pain.
The aim in using opioid drugs in chronic pain is optimal pain relief with a minimum of side effects. A rational approach requires understanding of the clinical pharmacology of opioids given by a variety of routes, for the differences between routes may be greater than the differences between drugs given by the same route. Those using opioids in chronic pain differentiate between their clinical ...
متن کاملOpioids and chronic neuropathic pain.
Chronic neuropathic pain is a serious problem resulting from injury to the central or peripheral nervous system; it affects more than 2 million Americans. Despite advances in our understanding of the pathophysiology and molecular biology of neuropathic pain, its clinical management remains disappointing and controversial. Antidepressants and anticonvulsants have been demonstrated to provide ana...
متن کاملOpioids for chronic noncancer pain
The number of available opioid preparations, each with differing chemical properties, structure and opioid receptor affinity, increases with time. The efficacy of these opioids in the treatment of pain arising from a diverse range of disorders is beyond question. With the passage of time, the list of those conditions where an opioid is recommended as a treatment option increases, and that list ...
متن کاملOpioids for chronic nonmalignant and neuropathic pain.
It is now two hundred years ago that theGerman pharmacist F.W. Sertürner isolated the first pure opium alkaloid (Sertürner, 1805, 1806, 1817) that he named ‘‘morphine’’. Up-to-now the later so-called opioids are still the mainstay in modern pharmacological treatment of acute and chronic pain. Driven by the growing awareness of an unacceptably widespread undertreatment of pain together with the ...
متن کاملOpioids in chronic non-malignant pain.
Key Highlights Pain, the 5 vital sign , is often under-treated. Optimize use of both drug and non-drug interventions. Pain reduction and improved function, and not pain elimination are the goals of drug therapy. Those with CNMP must be helped to refocus on positive, incremental gains. Multiple visits are often required. Opioids have a role in select patients; carefully assess and use a treatmen...
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ژورنال
عنوان ژورنال: Canadian Medical Association Journal
سال: 2012
ISSN: 0820-3946,1488-2329
DOI: 10.1503/cmaj.112-2001